Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | TSPO | P30536 | 2/20 | 0.33 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416598 | 0.85 | TSPO (0.42) | LTA4HHCRTR1HCRTR2TSPOTEAD3 | |
| SCHEMBL416578 | 0.85 | TSPO (0.42) | HCRTR1HCRTR2TSPOTEAD3 | |
| SCHEMBL420135 | 0.82 | TSPO (0.41) | TSPO | |
| SCHEMBL22210606 | 0.82 | LTA4H (0.33) | HTR6SIGMAR1LTA4HHCRTR1HCRTR2 | |
| SCHEMBL460215 | 0.81 | TSPO (0.56) | TSPO | |
| SCHEMBL6693579 | 0.73 | FABP4 (0.44) | HTR6HCRTR1HCRTR2TSPO | |
| SCHEMBL12748241 | 0.73 | TSPO (0.44) | TSPO | |
| SCHEMBL12748229 | 0.73 | TSPO (0.44) | TSPO | |
| SCHEMBL12748236 | 0.73 | TSPO (0.44) | TSPO | |
| SCHEMBL6694139 | 0.72 | TSPO (0.42) | HTR6HCRTR1HCRTR2TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452221-B | Enantiomer separation and purification of 2,3,4, 9-tetrahydro-1H-carbazole-4-carboxamide derivatives | 通用电气健康护理有限公司 | 2018-11-23 | — | — | CN | disclosed |