SCHEMBL28255167

SCHEMBL28255167

C=CCc1cc(Cl)ccc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR Q13258 1/20 0.47
PTGDR2 Q9Y5Y4 1/20 0.47
CYP3A4 P08684 3/20 0.42
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
MAPT P10636 5/20 0.41
THRB P10828 1/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
LMNA P02545 3/20 0.41
HIF1A Q16665 2/20 0.41
SLC22A1 O15245 1/20 0.41
USP2 O75604 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSPD1 P10809 1/20 0.41
HSPA5 P11021 1/20 0.41
IDO1 P14902 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28026745 0.82 CYP3A4 (0.43) CYP3A4MAPTMEN1KMT2ALMNA
SCHEMBL21728222 0.81 CYP3A4 (0.39) PTGDRPTGDR2CYP3A4MAPTMEN1
SCHEMBL2490536 0.80 GABRA1 (0.66) PTGDRPTGDR2CYP3A4GABRA1GABRB2
SCHEMBL6447941 0.80 CYP3A4 (0.42) CYP3A4MAPTMEN1KMT2ALMNA
SCHEMBL30976143 0.79 TAAR1 (0.50) GABRA1GABRB2MAPTLMNASMN1; SMN2
SCHEMBL170382 0.79 TAAR1 (0.50) GABRA1GABRB2MAPTLMNASMN1; SMN2
SCHEMBL15066541 0.79 PTGDR (0.50) PTGDRPTGDR2CYP3A4GABRA1GABRB2
SCHEMBL9003492 0.78 GABRA1 (0.49) CYP3A4GABRA1GABRB2MAPTMEN1
SCHEMBL2555304 0.78 ALDH1A1 (0.48) CYP3A4GABRA1GABRB2MAPTTHRB
SCHEMBL6588336 0.77 CYP3A4 (0.46) CYP3A4MAPTMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108863873-A A kind of sulphur allyl carbonate esters compound and preparation method thereof 台州学院 2018-11-23 CN disclosed