Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490405 | 0.92 | POLB (0.61) | POLBBIRC2ALDH1A1THRBCYP2C9 | |
| SCHEMBL9491800 | 0.92 | POLB (0.61) | POLBBIRC2ALDH1A1THRBCYP2C9 | |
| SCHEMBL9487005 | 0.92 | POLB (0.61) | POLBBIRC2ALDH1A1THRBCYP2C9 | |
| SCHEMBL28885763 | 0.91 | POLB (0.60) | POLBBIRC2ALDH1A1THRBCYP2C9 | |
| SCHEMBL28953193 | 0.91 | POLB (0.60) | POLBBIRC2ALDH1A1THRBCYP2C9 | |
| SCHEMBL25590532 | 0.91 | POLB (0.60) | POLBBIRC2ALDH1A1THRBCYP2C9 | |
| SCHEMBL7452621 | 0.89 | SIGMAR1 (0.58) | POLBSIGMAR1ALDH1A1THRBCYP2C9 | |
| SCHEMBL6821732 | 0.88 | ALDH1A1 (0.57) | POLBALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL4024431 | 0.88 | POLB (0.63) | POLBBIRC2ALDH1A1THRBCYP2C9 | |
| Hydrochloric Acid SCHEMBL9008918 | 0.87 | POLB (0.61) | POLBBIRC2ALDH1A1THRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929340-A | Proline boric acid compound and its preparation method and application | 北京大学 | 2018-12-04 | — | — | CN | disclosed |