SCHEMBL28255296

SCHEMBL28255296

Fc1ccccc1-c1cc2ccc3cccc4ccc(c1-c1ccccc1F)c2c34

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.47
AHR P35869 3/20 0.47
ERBB2 P04626 1/20 0.47
FYN P06241 1/20 0.47
MAOA P21397 1/20 0.47
ACHE P22303 1/20 0.47
ALDH1A1 P00352 6/20 0.40
HSD17B10 Q99714 6/20 0.40
HPGD P15428 5/20 0.40
TSHR P16473 5/20 0.40
MAPK1 P28482 3/20 0.40
CASP1 P29466 2/20 0.40
HIF1A Q16665 2/20 0.40
TP53 P04637 1/20 0.40
CASP7 P55210 1/20 0.40
THRB P10828 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
CYP3A4 P08684 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CYP1A1 P04798 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27499366 0.80 CYP1A2 (0.55) CYP1A2AHRERBB2FYNMAOA
SCHEMBL4449917 0.77 ERBB2 (0.44) CYP1A2AHRERBB2FYNMAOA
SCHEMBL28916632 0.72 CYP1A2 (0.49) CYP1A2AHRERBB2FYNMAOA
SCHEMBL27790192 0.72 CRHBP (0.39) CYP1A2AHRERBB2FYNMAOA
SCHEMBL4451069 0.71 CYP1A2 (0.52) CYP1A2AHRERBB2FYNMAOA
SCHEMBL16822385 0.71 CYP1A2 (0.61) CYP1A2AHRERBB2FYNMAOA
Hydrogen Sulfide SCHEMBL28320580 0.70 CYP1A2 (0.50) CYP1A2AHRERBB2FYNMAOA
Ammonia Solution, Strong SCHEMBL27495767 0.70 CYP1A2 (0.50) CYP1A2AHRERBB2FYNMAOA
SCHEMBL28340900 0.70 CYP1A2 (0.46) CYP1A2AHRERBB2FYNMAOA
SCHEMBL12205385 0.69 ALDH1A1 (0.55) CYP1A2AHRALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104693105-B Organic compound and organic light emitting diode using the same 乐金显示有限公司 2018-12-04 CN disclosed