Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833 | 0.89 | ALDH1A1 (0.58) | ALDH1A1CYP1A2CYP2A6NPC1POLB | |
| Ammonia Solution, Strong SCHEMBL28864729 | 0.87 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP2A6NPC1POLB | |
| SCHEMBL28254153 | 0.80 | MET (0.55) | ALDH1A1NPC1POLBRAB9AMET | |
| Quinoline SCHEMBL27593158 | 0.78 | CYP1A2 (0.59) | ALDH1A1CYP1A2CYP2A6NPC1POLB | |
| Quinoline SCHEMBL28313280 | 0.76 | ALDH1A1 (0.57) | ALDH1A1CYP1A2CYP2A6NPC1POLB | |
| Quinoline SCHEMBL28130961 | 0.76 | ALDH1A1 (0.74) | ALDH1A1CYP1A2NPC1POLBRAB9A | |
| SCHEMBL25354572 | 0.76 | DAO (0.57) | ALDH1A1NPC1POLBRAB9AMET | |
| SCHEMBL5528688 | 0.76 | ALDH1A1 (0.55) | ALDH1A1NPC1POLBRAB9AMET | |
| SCHEMBL29903898 | 0.76 | ALDH1A1 (0.55) | ALDH1A1NPC1POLBRAB9AMET | |
| SCHEMBL30173448 | 0.76 | DAO (0.57) | ALDH1A1NPC1POLBRAB9AMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912141-A | Gram-Negative bacillus inhibitor and its preparation and application | 中国医学科学院医药生物技术研究所 | 2018-11-30 | — | — | CN | claimed |