SCHEMBL30173448

SCHEMBL30173448

c1ccc(CCc2ccc3ncccc3c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.57
MET P08581 4/20 0.53
NPC1 O15118 3/20 0.53
POLB P06746 2/20 0.53
RAB9A P51151 2/20 0.53
ALDH1A1 P00352 3/20 0.50
MAPT P10636 2/20 0.50
KDM4E B2RXH2 1/20 0.50
TP53 P04637 1/20 0.50
HSP90AA1 P07900 1/20 0.50
HSP90AB1 P08238 1/20 0.50
TSHR P16473 1/20 0.50
CASP1 P29466 1/20 0.50
HTT P42858 1/20 0.50
ATM Q13315 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50
KCNH2 Q12809 1/20 0.50
HRH3 Q9Y5N1 1/20 0.50
HDAC3 O15379 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25354572 1.00 DAO (0.57) DAOMETNPC1POLBRAB9A
SCHEMBL13463756 0.93 DAO (0.51) DAOMETNPC1POLBRAB9A
SCHEMBL25752716 0.86 DAO (0.55) DAOMETNPC1POLBRAB9A
SCHEMBL27824234 0.86 MET (0.53) METNPC1POLBRAB9AALDH1A1
SCHEMBL2298312 0.85 DAO (0.53) DAOMETNPC1POLBRAB9A
SCHEMBL2597877 0.82 ALDH1A1 (0.59) DAOMETNPC1POLBRAB9A
SCHEMBL6961498 0.82 DAO (0.57) DAOMETNPC1POLBRAB9A
SCHEMBL252567 0.82 DAO (0.54) DAOMETNPC1POLBRAB9A
SCHEMBL5528688 0.82 ALDH1A1 (0.55) DAOMETNPC1POLBRAB9A
SCHEMBL3846360 0.82 DAO (0.54) DAOMETNPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115772058-B Reduction method of aromatic internal olefins 南通大学 2024-08-16 CN disclosed
CN-115772058-A Reduction method of aromatic internal olefin 南通大学 2023-03-10 CN disclosed