Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112473 | 0.88 | KIF11 (0.48) | KIF11CDK4CCND1KDM4EGAA | |
| SCHEMBL27276829 | 0.87 | KIF11 (0.65) | KIF11KDM4EGABRA1GABRG2GABRB3 | |
| SCHEMBL10131018 | 0.85 | KIF11 (0.48) | KIF11CDK4CCND1KDM4EGAA | |
| SCHEMBL21376875 | 0.84 | KIF11 (0.62) | KIF11KDM4EGAA | |
| SCHEMBL12001022 | 0.84 | CDK4 (0.57) | CDK4CCND1KDM4EGAAGABRA1 | |
| SCHEMBL17154708 | 0.84 | CDK4 (0.57) | CDK4CCND1KDM4EGAAGABRA1 | |
| SCHEMBL30300831 | 0.84 | CDK4 (0.57) | CDK4CCND1KDM4EGAAGABRA1 | |
| SCHEMBL149685 | 0.84 | CDK4 (0.57) | CDK4CCND1KDM4EGAAGABRA1 | |
| SCHEMBL3365890 | 0.84 | CDK4 (0.57) | CDK4CCND1KDM4EGAAGABRA1 | |
| SCHEMBL19041639 | 0.84 | CDK4 (0.57) | CDK4CCND1KDM4EGAAGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111433-A | A kind of organic electroluminescent compounds and application thereof and organic electroluminescence device | 北京鼎材科技有限公司 | 2019-01-01 | — | — | CN | disclosed |