Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417342 | 0.92 | KDM4E (0.76) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL197619 | 0.91 | RAB9A (0.72) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3335320 | 0.89 | KDM4E (0.71) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5636118 | 0.87 | CHEK2 (0.63) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3916753 | 0.86 | CHEK2 (0.65) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3367497 | 0.85 | KDM4E (0.82) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5634840 | 0.85 | NPC1 (0.91) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2248110 | 0.85 | SMN1; SMN2 (0.82) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3915300 | 0.85 | CHEK2 (0.66) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4188962 | 0.84 | MEN1 (0.76) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790219-A | Using lilotomab and177Lu-lilotomab satetraxetan treats non-Hodgkin lymphoma | 诺帝克纳诺维科特公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109642905-A | Using the method for the antibody in conjunction with C1 inactivated factor, the antibody in conjunction with c reactive protein and/or the antibody diagnosis in conjunction with complement component C4 and treating cancer | 丹纳基因有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-108939065-A | Method for raising antigen presentation | 诺帝克纳诺维科特公司 | 2018-12-07 | — | — | CN | disclosed |