SCHEMBL3417342

SCHEMBL3417342

c1ccc2[nH]c(-c3ccc(Oc4ccc(-c5nc6ccccc6[nH]5)cc4)cc3)nc2c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.76
NPC1 O15118 6/20 0.76
RAB9A P51151 6/20 0.76
ALDH1A1 P00352 6/20 0.76
SMN1; SMN2 Q16637 5/20 0.76
PKM P14618 3/20 0.76
GAA P10253 1/20 0.70
HPGD P15428 3/20 0.67
TP53 P04637 2/20 0.67
HSD17B10 Q99714 2/20 0.67
POLB P06746 1/20 0.67
MAPT P10636 1/20 0.67
GFER P55789 1/20 0.67
CHEK2 O96017 3/20 0.64
PKN1 Q16512 1/20 0.64
PKN2 Q16513 1/20 0.64
HPSE Q9Y251 1/20 0.62
ABCB11 O95342 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
HDAC6 Q9UBN7 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3335320 0.97 KDM4E (0.71) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL3367497 0.92 KDM4E (0.82) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL5634840 0.92 NPC1 (0.91) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL2248110 0.92 SMN1; SMN2 (0.82) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL28256337 0.92 NPC1 (0.66) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL13015025 0.91 NPC1 (0.88) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL14434505 0.91 CHEK2 (0.66) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL29386825 0.89 NPC1 (0.88) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL2178266 0.89 NPC1 (0.88) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL5636118 0.88 CHEK2 (0.63) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018128-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-06-25 US disclosed
US-20220119596-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-04-21 US disclosed
US-7696298-B2 Poly(arylenebenzimidazole) polymers and copolymers HAY ALLAN S 2010-04-13 US disclosed
US-7696298-B2 Poly(arylenebenzimidazole) polymers and copolymers HAY ALLAN S 2010-04-13 US disclosed
US-7696298-B2 Poly(arylenebenzimidazole) polymers and copolymers HAY ALLAN S 2010-04-13 US disclosed
US-20090131623-A1 Poly(arylenebenzimidazole) polymers and copolymers HAY ALLAN S 2009-05-21 US disclosed
US-20090131623-A1 Poly(arylenebenzimidazole) polymers and copolymers HAY ALLAN S 2009-05-21 US disclosed
US-20090131623-A1 Poly(arylenebenzimidazole) polymers and copolymers HAY ALLAN S 2009-05-21 US disclosed