Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083174 | 0.82 | LMNA (0.54) | KDM4ERAB9AHTTLMNAKMT2A | |
| SCHEMBL28257555 | 0.81 | RAB9A (0.63) | KDM4ERAB9AHTTLMNAHSPB1 | |
| SCHEMBL12050816 | 0.79 | HSPB1 (0.55) | RAB9AHTTLMNAHSPB1KMT2A | |
| SCHEMBL23323402 | 0.79 | RAB9A (0.52) | KDM4ERAB9AHTTLMNAHSPB1 | |
| SCHEMBL3502988 | 0.79 | LMNA (0.60) | KDM4ERAB9AHTTLMNAHSPB1 | |
| SCHEMBL20932230 | 0.78 | HSPB1 (0.82) | KDM4ERAB9AHTTLMNAHSPB1 | |
| SCHEMBL22032883 | 0.78 | LMNA (0.49) | KDM4EHTTLMNAHSPB1KMT2A | |
| SCHEMBL5569863 | 0.77 | MAPT (0.46) | HTTLMNAHSPB1KMT2AMAPT | |
| SCHEMBL24168084 | 0.76 | HTT (0.57) | RAB9AHTTLMNAHSPB1KMT2A | |
| SCHEMBL3997433 | 0.75 | HSPB1 (0.63) | KDM4ERAB9AHTTLMNAHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947918-B | Diamine monomer containing pyrazine structure and preparation method thereof, polyimide containing pyrazine structure and preparation method thereof | 吉林大学 | 2021-01-15 | — | — | CN | disclosed |
| CN-108947918-A | A kind of polyimides and preparation method thereof of diamine monomer of the structure containing pyrazine and preparation method thereof and a kind of structure containing pyrazine | 吉林大学 | 2018-12-07 | — | — | CN | disclosed |