2-Methoxybenzaldehyde

2-Methoxybenzaldehyde

SCHEMBL28257560

COc1ccccc1C=O.[NaH]

nearest known ligand 0.63

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
LMNA P02545 4/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2C9 P11712 1/20 0.63
CYP2C19 P33261 1/20 0.63
ERN1 O75460 2/20 0.62
TLR2 O60603 1/20 0.62
TLR1 Q15399 1/20 0.62
TLR6 Q9Y2C9 1/20 0.62
HPGD P15428 1/20 0.59
HTT P42858 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
KMT2A Q03164 2/20 0.55
GAA P10253 1/20 0.55
NFE2L2 Q16236 4/20 0.55
TFEB P19484 1/20 0.55
TRPA1 O75762 1/20 0.53
KDM4E B2RXH2 2/20 0.53
TDP1 Q9NUW8 2/20 0.52
MEN1 O00255 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Methoxybenzaldehyde SCHEMBL66490 0.98 ALDH1A1 (0.66) ALDH1A1LMNACYP1A2CYP2C9CYP2C19
2-Methoxybenzaldehyde SCHEMBL8469378 0.98 ALDH1A1 (0.66) ALDH1A1LMNACYP1A2CYP2C9CYP2C19
2-Methoxybenzaldehyde SCHEMBL29358929 0.98 ALDH1A1 (0.66) ALDH1A1LMNACYP1A2CYP2C9CYP2C19
2-Methoxybenzaldehyde SCHEMBL27337621 0.95 ALDH1A1 (0.63) ALDH1A1LMNACYP1A2CYP2C9CYP2C19
2-Methoxybenzaldehyde SCHEMBL28639538 0.95 ALDH1A1 (0.63) ALDH1A1LMNACYP1A2CYP2C9CYP2C19
2-Methoxybenzaldehyde SCHEMBL28954369 0.95 ALDH1A1 (0.63) ALDH1A1LMNACYP1A2CYP2C9CYP2C19
2-Methoxybenzaldehyde SCHEMBL27949860 0.95 ALDH1A1 (0.63) ALDH1A1LMNACYP1A2CYP2C9CYP2C19
2-Methoxybenzaldehyde SCHEMBL28193905 0.95 LMNA (0.63) ALDH1A1LMNACYP1A2CYP2C9CYP2C19
2-Methoxybenzaldehyde SCHEMBL16733637 0.90 ERN1 (0.61) ALDH1A1LMNACYP1A2CYP2C9CYP2C19
2-Methoxybenzaldehyde SCHEMBL11527176 0.88 NFE2L2 (0.61) ALDH1A1LMNACYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106146417-B A method of 4- aryl-NH-1,2,3- triazole is prepared using aldehyde sodium bisulfite adduct 海南师范大学 2018-12-04 CN disclosed