Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28923716 | 0.81 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1LMNAKMT2ACYP1A2 | |
| Ammonia Solution, Strong SCHEMBL28400831 | 0.80 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1LMNAKMT2ACYP1A2 | |
| SCHEMBL28103434 | 0.80 | HSD17B10 (0.48) | L3MBTL1LMNAKMT2ACYP1A2CYP2C9 | |
| Ethyl Nicotinate SCHEMBL29958752 | 0.78 | L3MBTL1 (0.71) | ALDH1A1L3MBTL1LMNAKMT2ATDP1 | |
| Ethyl Nicotinate SCHEMBL8164637 | 0.78 | L3MBTL1 (0.71) | ALDH1A1L3MBTL1LMNAKMT2ATDP1 | |
| Ethyl Nicotinate SCHEMBL1330922 | 0.78 | L3MBTL1 (0.71) | ALDH1A1L3MBTL1LMNAKMT2ATDP1 | |
| Ethyl Nicotinate SCHEMBL24853 | 0.78 | L3MBTL1 (0.71) | ALDH1A1L3MBTL1LMNAKMT2ATDP1 | |
| Ethyl Nicotinate SCHEMBL8071110 | 0.77 | L3MBTL1 (0.69) | ALDH1A1L3MBTL1LMNAKMT2ATDP1 | |
| Ethyl Nicotinate SCHEMBL11484012 | 0.77 | L3MBTL1 (0.69) | ALDH1A1L3MBTL1LMNAKMT2ATDP1 | |
| Ethyl Nicotinate SCHEMBL9408506 | 0.77 | L3MBTL1 (0.69) | ALDH1A1L3MBTL1LMNAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108948212-A | Long-actingization oxyntomodulin (OXM) hybrid peptide and the preparation method and application thereof | 中国药科大学 | 2018-12-07 | — | — | CN | claimed |
| CN-107522669-B | 1 antagonist of transient receptor potential vanillic acid hypotype and its preparation method and application | 重庆美莱德生物医药有限公司 | 2019-12-03 | — | — | CN | disclosed |
| CN-107522668-B | TRPV1 antagonist and its preparation method and application | 重庆医科大学 | 2019-12-03 | — | — | CN | disclosed |
| CN-106804107-B | New benzodiazepine * analog derivative and application thereof | 江苏恩华络康药物研发有限公司 | 2019-03-12 | — | — | CN | disclosed |