Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458186 | 0.98 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10PDCD1 | |
| SCHEMBL2567219 | 0.85 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL10636097 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10PDCD1 | |
| SCHEMBL3416851 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL1127360 | 0.81 | KMT2A (0.65) | KDM4EALDH1A1HPGDHSD17B10SIRT2 | |
| SCHEMBL11017105 | 0.80 | CA1 (0.54) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL5798626 | 0.79 | KMT2A (0.45) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL22638691 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10SIRT2 | |
| SCHEMBL5279632 | 0.78 | ALDH1A1 (0.79) | KDM4EALDH1A1HPGDHSD17B10SIRT2 | |
| SCHEMBL3353838 | 0.77 | CA2 (0.57) | KDM4EALDH1A1HPGDHSD17B10PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108938615-A | Benzene sulfonamido benzamide compound is used to treat the purposes of non-alcohol fatty liver | 中国医学科学院医药生物技术研究所 | 2018-12-07 | — | — | CN | disclosed |