Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28255164 | 0.84 | GPR35 (0.37) | KMT2AALDH1A1ALOX15KDM4EHPGD | |
| SCHEMBL7869937 | 0.83 | KMT2A (0.65) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3684999 | 0.83 | CA1 (0.44) | KMT2AALDH1A1ALOX15KDM4EHPGD | |
| SCHEMBL2567219 | 0.82 | ALDH1A1 (0.55) | KMT2AALDH1A1ALOX15KDM4EHPGD | |
| SCHEMBL11017105 | 0.81 | CA1 (0.54) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3458186 | 0.81 | KDM4E (0.55) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9850093 | 0.80 | KMT2A (0.60) | KMT2AALDH1A1KDM4EHPGDMEN1 | |
| Benzene SCHEMBL28257697 | 0.79 | KDM4E (0.54) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11123980 | 0.79 | ALDH1A1 (0.47) | KMT2AALDH1A1ALOX15KDM4EHPGD | |
| SCHEMBL594 | 0.79 | CA2 (0.53) | KMT2AALDH1A1ALOX15MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293297-A1 | Cyanofluoropyrrolidine derviative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1627870-A1 | CYANOFLUOROPYRROLIDINE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293297-A1 | Cyanofluoropyrrolidine derviative | DPP4, DPP3, NPY4R | KMT2A 4122/4885ALDH1A1 3197/4885ALOX15 3754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.