Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314986 | 0.82 | INSR (0.65) | INSRMAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL1506734 | 0.82 | INSR (0.65) | INSRMAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28257868 | 0.76 | KDM4E (0.43) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| Naphthalene SCHEMBL11589769 | 0.74 | CYP2A6 (0.36) | MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL1306156 | 0.74 | INSR (0.69) | INSRMAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL1306153 | 0.74 | INSR (0.69) | INSRMAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6655466 | 0.72 | HPGD (0.54) | INSRMAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5206443 | 0.72 | — | — | |
| SCHEMBL28234601 | 0.72 | INSR (0.54) | INSRMAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6998648 | 0.70 | INSR (0.49) | INSRMAPTKMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864152-A | A kind of preparation method and application of benzo double thiazole class azo-compound | 山西大同大学 | 2018-11-23 | — | — | CN | disclosed |