Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | ILK | Q13418 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28257867 | 0.76 | INSR (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2554756 | 0.74 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL687108 | 0.73 | KDM4E (0.61) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10884670 | 0.73 | PRKCI (0.35) | KDM4EALDH1A1MAPTGLARAB9A | |
| SCHEMBL687432 | 0.72 | ILK (0.56) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL686439 | 0.71 | KDM4E (0.54) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10803025 | 0.71 | — | — | |
| SCHEMBL715973 | 0.71 | ILK (0.54) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5152077 | 0.70 | LMNA (0.36) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10891792 | 0.70 | MEN1 (0.33) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864152-A | A kind of preparation method and application of benzo double thiazole class azo-compound | 山西大同大学 | 2018-11-23 | — | — | CN | disclosed |