SCHEMBL1306156

SCHEMBL1306156

c1ccc(N=Nc2nc3ccccc3s2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INSR P06213 4/20 0.69
MAPT P10636 7/20 0.51
KMT2A Q03164 4/20 0.51
NPC1 O15118 4/20 0.51
RAB9A P51151 4/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
MCL1 Q07820 2/20 0.51
CASP3 P42574 2/20 0.51
SENP7 Q9BQF6 2/20 0.51
SENP6 Q9GZR1 2/20 0.51
MEN1 O00255 3/20 0.45
HPGD P15428 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
MAPK1 P28482 1/20 0.45
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
ADRA2A P08913 1/20 0.44
FBP1 P09467 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
DRD2 P14416 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1306153 1.00 INSR (0.69) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL31314986 0.90 INSR (0.65) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL1506734 0.90 INSR (0.65) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL6556231 0.86 INSR (0.67) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL9869708 0.86 INSR (0.67) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL4983319 0.85 INSR (0.51) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL8390776 0.82 INSR (1.00) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL8390778 0.82 INSR (1.00) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL6655466 0.80 HPGD (0.54) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL28234601 0.79 INSR (0.54) INSRMAPTKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2153853-B1 Composition of indicator for detecting sterilization NICHU GIKEN KOGYO KK (JP) 2017-05-03 EP claimed
EP-2153853-A1 Composition of indicator for detecting sterilization Nichiyu Giken Kogyo Co., Ltd. (JP) 2010-02-17 EP claimed
EP-0819305-B1 LIQUID CRYSTAL OPTICAL STORAGE MEDIUM WITH GRAY SCALE ELSICON INC (US) 2004-11-17 EP claimed
US-5846452-A Liquid crystal optical storage medium with gray scale ALLIANT TECHSYSTEMS INC. (US) 1998-12-08 US claimed
EP-0387059-B1 Process of aligning liquid crystal media HERCULES INC (US) 1998-06-10 EP claimed
EP-0819305-A1 LIQUID CRYSTAL OPTICAL STORAGE MEDIUM WITH GRAY SCALE ALLIANT TECHSYSTEMS INC. (US) 1998-01-21 EP claimed
WO-1996031876-A1 LIQUID CRYSTAL OPTICAL STORAGE MEDIUM WITH GRAY SCALE ALLIANT TECHSYSTEMS INC. (US) 1996-10-10 WO claimed
US-5032009-A Polarized light exposure HERCULES INCORPORATED (US) 1991-07-16 US claimed
US-4974941-A Process of aligning and realigning liquid crystal media HERCULES INCORPORATED (US) 1990-12-04 US claimed
EP-0387059-A2 Process of aligning liquid crystal media HERCULES INCORPORATED (US) 1990-09-12 EP claimed
EP-0203567-B1 DISAZO DYES AND DYEING METHOD USING THE SAME MITSUBISHI KASEI CORPORATION (JP) 1989-02-08 EP claimed
EP-0203567-A2 Disazo dyes and dyeing method using the same MITSUBISHI KASEI CORPORATION (JP) 1986-12-03 EP claimed
US-12594264-B2 Modulators of alpha-synuclein proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-04-07 US disclosed
US-12044872-B2 Method for generating alignment on top of a liquid crystal polymer material Rolic Technologies AG (CH) 2024-07-23 US disclosed
CN-118259397-A Positive c-plate retarder capable of photoinduced alignment 罗利克技术有限公司 2024-06-28 CN disclosed
CN-114286852-B Composition of polymerizable liquid crystal 罗利克技术有限公司 2024-06-25 CN disclosed
US-4841029-A WATER SOLUBLE, COLORFAST FIBER REACTIVE DYE FOR CELLULOSE POLYETHER FABRICS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1989-06-20 US disclosed
EP-0203567-B1 DISAZO DYES AND DYEING METHOD USING THE SAME MITSUBISHI KASEI CORPORATION (JP) 1989-02-08 EP disclosed
EP-0203567-A2 Disazo dyes and dyeing method using the same MITSUBISHI KASEI CORPORATION (JP) 1986-12-03 EP disclosed
US-4039524-A Keto-amido containing phenylazo benzothiazole dyestuffs GAF CORPORATION (US) 1977-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12594264-B2 Modulators of alpha-synuclein proteolysis and associated methods of use ADRM1, CRBN, SNCA INSR 3520/4885MAPT 210/4885KMT2A 1763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.