Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 4/20 | 0.63 |
| ▸ | CTSL | P07711 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | MAX | P61244 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316504 | 0.93 | CTSV (0.61) | CTSVCTSLPOLBSENP8SENP7 | |
| SCHEMBL4222265 | 0.89 | CTSV (0.58) | CTSVCTSLPOLBSENP8SENP7 | |
| SCHEMBL31235825 | 0.88 | CTSV (0.60) | CTSVCTSLPOLBSENP8SENP7 | |
| SCHEMBL582235 | 0.88 | CTSV (0.60) | CTSVCTSLPOLBSENP8SENP7 | |
| SCHEMBL19035902 | 0.88 | CTSV (0.57) | CTSVCTSLPOLBSENP8SENP7 | |
| SCHEMBL873861 | 0.87 | CTSV (0.60) | CTSVCTSLSENP8SENP7SENP6 | |
| SCHEMBL159283 | 0.87 | CTSV (0.60) | CTSVCTSLSENP8SENP7SENP6 | |
| SCHEMBL7116860 | 0.87 | POLB (0.56) | CTSVCTSLPOLBCYP19A1ABCB1 | |
| SCHEMBL27654714 | 0.86 | CTSV (0.58) | CTSVCTSLPOLBSENP8SENP7 | |
| SCHEMBL2722340 | 0.85 | CTSV (0.60) | CTSVCTSLPOLBFOLH1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693634-B | Compound and application thereof | 清华大学 | 2018-12-11 | — | — | CN | disclosed |