Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 5/20 | 0.61 |
| ▸ | CTSL | P07711 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19035902 | 0.95 | CTSV (0.57) | CTSVCTSLPOLBL3MBTL1SENP8 | |
| SCHEMBL873861 | 0.94 | CTSV (0.60) | CTSVCTSLSENP8SENP7SENP6 | |
| SCHEMBL159283 | 0.94 | CTSV (0.60) | CTSVCTSLSENP8SENP7SENP6 | |
| SCHEMBL28257932 | 0.93 | CTSV (0.63) | CTSVCTSLPOLBL3MBTL1SENP8 | |
| SCHEMBL4222265 | 0.91 | CTSV (0.58) | CTSVCTSLPOLBL3MBTL1SENP8 | |
| SCHEMBL27654714 | 0.91 | CTSV (0.58) | CTSVCTSLPOLBL3MBTL1SENP8 | |
| SCHEMBL31151917 | 0.90 | CTSV (0.53) | CTSVCTSLPOLBL3MBTL1SENP8 | |
| SCHEMBL582235 | 0.89 | CTSV (0.60) | CTSVCTSLPOLBL3MBTL1SENP8 | |
| SCHEMBL31235825 | 0.89 | CTSV (0.60) | CTSVCTSLPOLBL3MBTL1SENP8 | |
| SCHEMBL31151927 | 0.89 | CTSV (0.52) | CTSVCTSLPOLBL3MBTL1SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484881-B1 | Heteroaroyl derivatives of monocyclic beta-lactam antibiotics | SQUIBB & SONS INC (US) | 1999-04-07 | — | — | EP | disclosed |
| US-5705645-A | Hereroaryl derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5420277-A | BACTERICIDE INTERMEDIATES | E. R. SQUIBB & SONS, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5290929-A | Heteroaryl derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| EP-0484881-A2 | Heteroaroyl derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1992-05-13 | — | — | EP | disclosed |