SCHEMBL159283

SCHEMBL159283

COc1cc(C(=O)O)c([N+](=O)[O-])cc1OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSV O60911 6/20 0.60
CTSL P07711 6/20 0.60
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
ALDH1A1 P00352 1/20 0.57
LMNA P02545 2/20 0.54
ABCB1 P08183 1/20 0.52
SRD5A1 P18405 2/20 0.51
SRD5A2 P31213 2/20 0.51
KDM4E B2RXH2 1/20 0.51
MAPT P10636 2/20 0.51
GAA P10253 1/20 0.50
HTR1A P08908 1/20 0.49
ADRA1D P25100 1/20 0.49
ADRA1A P35348 1/20 0.49
ADRA1B P35368 1/20 0.49
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL873861 1.00 CTSV (0.60) CTSVCTSLMEN1KMT2AALDH1A1
SCHEMBL16053347 0.94 CTSV (0.56) CTSVCTSLMEN1KMT2AALDH1A1
SCHEMBL8316504 0.94 CTSV (0.61) CTSVCTSLMEN1KMT2AALDH1A1
SCHEMBL38657998 0.93 LMNA (0.64) CTSVCTSLMEN1KMT2AALDH1A1
SCHEMBL31151917 0.92 CTSV (0.53) CTSVCTSLMEN1KMT2AALDH1A1
SCHEMBL340310 0.91 MEN1 (0.56) CTSVCTSLMEN1KMT2AALDH1A1
SCHEMBL13936617 0.91 MEN1 (0.56) CTSVCTSLMEN1KMT2AALDH1A1
SCHEMBL1013111 0.90 MEN1 (0.57) CTSVCTSLMEN1KMT2AALDH1A1
SCHEMBL3420694 0.90 LMNA (0.55) CTSVCTSLMEN1KMT2AALDH1A1
SCHEMBL2063806 0.90 MEN1 (0.57) CTSVCTSLMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567346-A Bismaleimide and preparation method thereof, and method for preparing aviation heat-resistant die plate 重庆渝启欣科技发展有限公司 2024-02-20 CN claimed
US-8309726-B2 Substituted piperazine compounds of formula 8 COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-11-13 US claimed
EP-2150527-B1 ANTHRANILIC ACID DERIVATIVE AS ANTICANCER AGENT AND A PROCESS FOR THE PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2011-01-19 EP claimed
EP-2150527-A2 ANTHRANILIC ACID DERIVATIVE AS ANTICANCER AGENT AND A PROCESS FOR THE PREPARATION THEREOF Council of Scientific & Industrial Research (IN) 2010-02-10 EP claimed
US-20100016589-A1 Novel Anthranilic Acid Derivative as Potential Anticancer Agent and a Process for the Preparation Thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-01-21 US claimed
WO-2008114275-A2 ANTHRANILIC ACID DERIVATIVES AS ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2008-09-25 WO claimed
US-6660856-B2 A group of potent, naturally occurring anti-tumor antibiotics produced by Streptomyces species KAOHSIUNG MEDICAL UNIVERSITY (TW) 2003-12-09 US claimed
US-20030187253-A1 SYNTHESIS OF PYRROLO[2,1-C][1,4]BENZODIAZEPINE ANALOGUES KAOHSIUNG MEDICAL UNIVERSITY 2003-10-02 US claimed
WO-2026098315-A1 HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2026-05-15 WO disclosed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US disclosed
US-12606634-B2 Antibody-pyrrolobenzodiazepine derivative conjugate which binds caludin-6 and claudin-9 DAIICHI SANKYO COMPANY, LIMITED (JP) 2026-04-21 US disclosed
US-12583857-B2 Anti-liferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines PHEON THERAPEUTICS LTD (GB) 2026-03-24 US disclosed
US-12508321-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-30 US disclosed
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-16 US disclosed
US-20030187253-A1 SYNTHESIS OF PYRROLO[2,1-C][1,4]BENZODIAZEPINE ANALOGUES KAOHSIUNG MEDICAL UNIVERSITY 2003-10-02 US disclosed
EP-1109811-B1 PYRROLOBENZODIAZEPINES SPIROGEN LTD (GB) 2003-08-06 EP disclosed
US-6562806-B1 A prodrug may be converted into an antitumour agent under the influence of an enzyme that is linked to a monoclonal antibody so that it can bind to a tumour associated antigen SPIROGEN LIMITED (GB) 2003-05-13 US disclosed
EP-1109811-A2 PYRROLOBENZODIAZEPINES Spirogen Limited (GB) 2001-06-27 EP disclosed
WO-2000012507-A2 PYRROLOBENZODIAZEPINES SPIROGEN LIMITED (GB) 2000-03-09 WO disclosed
US-4950674-A Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment A. H. ROBINS COMPANY, INCORPORATED (US) 1990-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12508321-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD4, CD2, B2M CTSV 1958/4885CTSL 1558/4885MEN1 780/4885
US-12606634-B2 Antibody-pyrrolobenzodiazepine derivative conjugate which binds caludin-6 and claudin-9 SIGLEC9, DSG1, VSIG8 CTSV 2087/4885CTSL 2637/4885MEN1 3455/4885
US-20030187253-A1 SYNTHESIS OF PYRROLO[2,1-C][1,4]BENZODIAZEPINE ANALOGUES GABRA4, GABRP, GABRD CTSV 3238/4885CTSL 2018/4885MEN1 1230/4885
US-20100016589-A1 Novel Anthranilic Acid Derivative as Potential Anticancer Agent and a Process for the Preparation Thereof AADAC, API5, APEH CTSV 3271/4885CTSL 2665/4885MEN1 3412/4885
US-12583857-B2 Anti-liferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines CNR1, MTNR1B, MTNR1A CTSV 2478/4885CTSL 2074/4885MEN1 2948/4885
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM CTSV 2654/4885CTSL 925/4885MEN1 2291/4885
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS DCLRE1A, CCR3, CCR8 CTSV 1754/4885CTSL 383/4885MEN1 2393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.