Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 15/20 | 0.56 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 11/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28256724 | 0.87 | USP28 (0.53) | USP28NAMPTUSP25DRD2 | |
| SCHEMBL28256718 | 0.86 | USP28 (0.52) | USP28NAMPTUSP25DRD2 | |
| SCHEMBL19212421 | 0.83 | SRPK1 (0.49) | NAMPTDRD2 | |
| SCHEMBL22957300 | 0.81 | NAMPT (0.51) | USP28NAMPTUSP25 | |
| SCHEMBL20139813 | 0.80 | NAMPT (0.42) | USP28NAMPTUSP25DRD2 | |
| SCHEMBL28682343 | 0.80 | SIGMAR1 (0.44) | USP28NAMPTDRD2 | |
| SCHEMBL28258242 | 0.79 | USP28 (0.46) | USP28NAMPTUSP25DRD2 | |
| SCHEMBL10232981 | 0.78 | TRPV1 (0.52) | NAMPT | |
| SCHEMBL10232975 | 0.78 | NAMPT (0.44) | NAMPTDRD2 | |
| SCHEMBL10232997 | 0.76 | TRPV1 (0.42) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-A | Thienopyridine formamide as ubiquitin-specific protease inhibitor | 福马治疗股份有限公司 | 2018-12-21 | — | — | CN | disclosed |