Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306573 | 0.81 | MAOA (0.50) | CRBNHSD17B10MRGPRX1ALDH1A1KDM4E | |
| SCHEMBL3965575 | 0.81 | CRBN (0.48) | CRBNHSD17B10MRGPRX1ALDH1A1KDM4E | |
| SCHEMBL19857573 | 0.80 | LCK (0.50) | CRBNHSD17B10MRGPRX1ALDH1A1KDM4E | |
| SCHEMBL2260801 | 0.79 | CRBN (0.46) | CRBNMRGPRX1ALDH1A1MAOAHPGD | |
| SCHEMBL19437254 | 0.76 | PIM1 (0.41) | HSD17B10ALDH1A1KDM4EMAOAGAA | |
| SCHEMBL17978294 | 0.76 | PRKDC (0.45) | PLK1HSD17B10ALDH1A1KDM4EMTNR1A | |
| SCHEMBL3455539 | 0.76 | NPC1 (0.60) | CRBNMRGPRX1KMT2ANPC1RAB9A | |
| SCHEMBL30088638 | 0.76 | CRBN (0.61) | CRBNMRGPRX1ALDH1A1KDM4ENPC1 | |
| SCHEMBL14401689 | 0.75 | ALDH1A1 (0.51) | CRBNMRGPRX1ALDH1A1KDM4EMAOA | |
| SCHEMBL3306362 | 0.74 | CXCR5 (0.62) | ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884083-A | Benzo [ B ] furans as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2018-11-23 | — | — | CN | disclosed |