Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | MAOA | P21397 | 5/20 | 0.37 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 5/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 5/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212239 | 0.80 | MAPT (0.57) | GPR119NAMPTMAPTALDH1A1LMNA | |
| SCHEMBL27615060 | 0.80 | GFER (0.54) | ITGB3ITGA2BGPR119NAMPTMAPT | |
| SCHEMBL28258189 | 0.79 | GAA (0.41) | KDM1AMAOANAMPTMAPTALDH1A1 | |
| SCHEMBL27859336 | 0.77 | DRD2 (0.48) | GPR119NAMPTMAPTALDH1A1LMNA | |
| SCHEMBL28331829 | 0.77 | ALDH1A1 (0.51) | MAPTALDH1A1LMNAGFER | |
| SCHEMBL27605764 | 0.77 | AKR1C3 (0.47) | ITGB3ITGA2BGPR119NAMPTMAPT | |
| SCHEMBL27981599 | 0.77 | GPR119 (0.49) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL28675131 | 0.75 | ALDH1A1 (0.54) | MAOBMAPTALDH1A1LMNAPOLB | |
| SCHEMBL27981818 | 0.75 | CA12 (0.54) | MAOBNAMPTMAPTLMNAMEN1 | |
| SCHEMBL27908416 | 0.74 | ALDH1A1 (0.56) | MAPTALDH1A1LMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-A | Thienopyridine formamide as ubiquitin-specific protease inhibitor | 福马治疗股份有限公司 | 2018-12-21 | — | — | CN | disclosed |