Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21896387 | 0.74 | KDM4E (0.49) | KMT2A | |
| SCHEMBL21895816 | 0.74 | PTGFR (0.43) | KMT2AMAPK1CA2MEN1ALDH1A1 | |
| SCHEMBL21896388 | 0.74 | KDM4E (0.49) | KMT2A | |
| Diethylamine SCHEMBL28327490 | 0.73 | CA2 (0.63) | MAPK1CA2MAPT | |
| SCHEMBL28295290 | 0.73 | TMEM97 (0.50) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL20562178 | 0.72 | GRIK1 (0.54) | EPHX1MAPK1CA2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11825996 | 0.70 | GRIK1 (0.53) | EPHX1MAPK1CA2ALDH1A1MAPT | |
| SCHEMBL14632705 | 0.70 | GRIK1 (0.56) | EPHX1KMT2AMAPK1CA2MEN1 | |
| SCHEMBL14996258 | 0.70 | ALDH1A1 (0.51) | KMT2AMAPK1CA2MEN1ALDH1A1 | |
| SCHEMBL593706 | 0.69 | CA2 (0.81) | MAPK1CA2FOLH1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876955-B | Arginase inhibitor and its treatment use | 马尔斯公司 | 2018-11-23 | — | — | CN | disclosed |