SCHEMBL28258477

SCHEMBL28258477

Cc1cc(C)c(C(=O)c2ccccc2C(=O)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
MEN1 O00255 2/20 0.47
HPGD P15428 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MCOLN3 Q8TDD5 1/20 0.47
ALDH1A1 P00352 2/20 0.46
POLB P06746 1/20 0.46
AKR1C3 P42330 1/20 0.46
METAP2 P50579 1/20 0.44
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
ABCB1 P08183 1/20 0.41
CRHR1 P34998 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
HSD11B1 P28845 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28242774 0.98 KMT2A (0.46) KMT2AMEN1HPGDNPSR1LMNA
SCHEMBL6964513 0.92 AKR1C3 (0.58) KMT2AMEN1LMNAALDH1A1POLB
SCHEMBL5472754 0.92 KMT2A (0.45) KMT2AMEN1HPGDNPSR1LMNA
SCHEMBL7837520 0.91 ALDH1A1 (0.42) KMT2AMEN1HPGDNPSR1LMNA
SCHEMBL28084280 0.88 KMT2A (0.43) KMT2AMEN1HPGDNPSR1LMNA
SCHEMBL11073625 0.88 HDAC7 (0.46) KMT2AMEN1NPSR1LMNASMN1; SMN2
SCHEMBL8067275 0.87 KMT2A (0.60) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL11526534 0.87 CES2 (0.48) KMT2AMEN1HPGDNPSR1LMNA
SCHEMBL98046 0.87 KMT2A (0.42) KMT2AMEN1HPGDNPSR1LMNA
SCHEMBL7172401 0.85 KMT2A (0.42) KMT2AMEN1HPGDNPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109786812-A A kind of photo-cured solid composite electrolyte and preparation method thereof 北京理工大学 2019-05-21 CN claimed
CN-109207051-A A kind of LED low energy solidification hot water dissolving's glass protection glue and preparation method thereof 广东鑫皇冠新材料有限公司 2019-01-15 CN claimed
CN-108997821-A UV-LED ink and its curing method 苏州汉力新材料有限公司 2018-12-14 CN claimed
CN-110402258-A Actinic-radiation curable composition, solidfied material and film DAINIPPON INK & CHEMICALS 2019-11-01 CN disclosed
CN-104969126-B Negative-type photosensitive coloured composition, cured film, the manufacturing method of touch panel light-shielding pattern and touch panel 东丽株式会社 2019-10-01 CN disclosed
CN-109957368-A A kind of LED-UV solidification Optical adhesive composition, preparation method and its solidify coating 比亚迪股份有限公司 2019-07-02 CN disclosed
CN-109328198-A Actinic-radiation curable composition and the film for using it DIC株式会社 2019-02-12 CN disclosed
CN-109310582-A Dental composition 登特斯普伊德特雷有限公司 2019-02-05 CN disclosed
CN-109312012-A Actinic-radiation curable composition and the film for using it DIC株式会社 2019-02-05 CN disclosed
CN-108949091-A A kind of ultraviolet-curing adhesive composition and manufacture craft 深圳市宝力新材料有限公司 2018-12-07 CN disclosed
CN-105814663-B Method for manufacturing structure using step-and-repeat imprint technique 综研化学株式会社 2018-06-08 CN disclosed