SCHEMBL7837520

SCHEMBL7837520

Cc1cc(C)c(C(=O)c2ccccc2C(N)=O)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.42
HPGD P15428 6/20 0.42
KDM4E B2RXH2 4/20 0.42
MAPT P10636 2/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
PARP1 P09874 2/20 0.41
RAB9A P51151 1/20 0.40
POLB P06746 1/20 0.40
METAP2 P50579 1/20 0.40
GAA P10253 2/20 0.40
USP2 O75604 1/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28258477 0.91 KMT2A (0.47) ALDH1A1HPGDKMT2AMEN1LMNA
SCHEMBL28242774 0.89 KMT2A (0.46) ALDH1A1HPGDKMT2AMEN1LMNA
SCHEMBL6964513 0.84 AKR1C3 (0.58) ALDH1A1KDM4EHSD17B10KMT2AMEN1
SCHEMBL5472754 0.83 KMT2A (0.45) ALDH1A1HPGDKMT2AMEN1LMNA
SCHEMBL7837115 0.81 NFE2L2 (0.46) ALDH1A1HPGDKDM4EKMT2ANPSR1
SCHEMBL7849103 0.81 NPSR1 (0.46) ALDH1A1HPGDKDM4ETSHRHSD17B10
SCHEMBL28084280 0.80 KMT2A (0.43) ALDH1A1HPGDMAPTKMT2AMEN1
SCHEMBL11073625 0.79 HDAC7 (0.46) KDM4EKMT2AMEN1LMNASMN1; SMN2
SCHEMBL11526534 0.79 CES2 (0.48) ALDH1A1HPGDKDM4EMAPTTSHR
SCHEMBL8067275 0.79 KMT2A (0.60) ALDH1A1HPGDKDM4EMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6328793-B1 FOR USE IN INK JET PRINTING PROCESSES, INCLUDING PIEZOELECTRIC INK JET PRINTING, ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-12-11 US claimed
US-6328793-B1 FOR USE IN INK JET PRINTING PROCESSES, INCLUDING PIEZOELECTRIC INK JET PRINTING, ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-12-11 US disclosed