Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | AGER | Q15109 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13810705 | 0.81 | POLB (0.74) | L3MBTL1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL13810726 | 0.81 | POLB (0.74) | L3MBTL1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL11711176 | 0.81 | POLB (0.74) | L3MBTL1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL267463 | 0.80 | LMNA (0.68) | L3MBTL1KDM4ELMNACYP2D6TSHR | |
| SCHEMBL11547527 | 0.79 | KDM4E (0.57) | L3MBTL1KDM4ELMNACYP2D6TSHR | |
| SCHEMBL22640151 | 0.79 | KDM4E (0.57) | L3MBTL1KDM4ELMNACYP2D6TSHR | |
| SCHEMBL11240406 | 0.79 | L3MBTL1 (0.97) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL4577971 | 0.79 | L3MBTL1 (0.97) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL3970369 | 0.79 | L3MBTL1 (0.97) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL14064868 | 0.77 | LMNA (0.67) | L3MBTL1KDM4ELMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102428-B | Novel DPP-IV inhibitors | DNJ制药有限公司 | 2018-11-16 | — | — | CN | disclosed |