SCHEMBL28258586

SCHEMBL28258586

CCN(CC)Cc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.55
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
RORC P51449 1/20 0.45
LMNA P02545 1/20 0.43
CA12 O43570 4/20 0.43
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
NT5E P21589 1/20 0.42
ACHE P22303 1/20 0.42
CA4 P22748 2/20 0.41
CNR2 P34972 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11614386 0.85 MCHR1 (0.61) RORCLMNAALDH1A1CNR2
SCHEMBL5352393 0.80 CNR2 (0.55) ALDH1A1TSHRCNR2
SCHEMBL3237375 0.80 AOC3 (0.55) HRH3
SCHEMBL6209059 0.79 LMNA (0.42) HDAC8HDAC6RORCLMNAALDH1A1
SCHEMBL10610047 0.79 POLB (0.45) HRH3LMNACA12CA1CA2
Phenolsulfonic Acid SCHEMBL14119913 0.78 LMNA (0.68) LMNACA12CA1CA2ALDH1A1
SCHEMBL593976 0.78 ALDH1A1 (0.47) LMNACA12CA1CA2ALDH1A1
SCHEMBL7768079 0.78 HRH3 (0.84) HRH3HDAC8HDAC6CNR2
SCHEMBL1563242 0.77 CA2 (0.61) LMNACA2ALDH1A1TSHRNT5E
SCHEMBL93796 0.77 CA2 (0.61) LMNACA2ALDH1A1TSHRNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108779356-A ink 富士胶片株式会社 2018-11-09 CN disclosed