Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.37 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | PPARD | Q03181 | 5/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873778 | 0.95 | PTGS1 (0.47) | PTGS1PTGS2ENPEPGSTK1AKR1B1 | |
| SCHEMBL28406949 | 0.94 | PTGS1 (0.50) | PTGS1PTGS2GSTK1TSHRFFAR4 | |
| SCHEMBL2494888 | 0.90 | PTGS1 (0.40) | PTGS1PTGS2ENPEPALDH1A1HSD17B10 | |
| SCHEMBL3962791 | 0.84 | FFAR4 (0.51) | PTGS1PTGS2AKR1B1TSHRFFAR4 | |
| SCHEMBL7053269 | 0.84 | FFAR4 (0.47) | PTGS1PTGS2AKR1B1TSHRFFAR4 | |
| SCHEMBL17924843 | 0.81 | MGLL (0.34) | PTGS1PTGS2ALDH1A1 | |
| SCHEMBL24692227 | 0.80 | MGLL (0.42) | PTGS1PTGS2TSHRALDH1A1 | |
| SCHEMBL326701 | 0.79 | PTGS1 (0.47) | PTGS1PTGS2ENPEPGSTK1ALDH1A1 | |
| SCHEMBL22972984 | 0.79 | MGLL (0.46) | PTGS1PTGS2ALDH1A1MEN1KMT2A | |
| SCHEMBL28128591 | 0.78 | PTGS1 (0.41) | PTGS1PTGS2ENPEPGSTK1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110066335-A | Anti-CD 40 antibodies and its application method | 埃派斯进有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-109265552-A | Anti-CD 40 antibodies and its application method | 埃派斯进有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-104918957-B | anti-CD 40 antibodies and methods of use thereof | 埃派斯进有限公司 | 2018-11-16 | — | — | CN | disclosed |