Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARD | Q03181 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28406949 | 0.98 | PTGS1 (0.50) | PTGS1PTGS2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL28258643 | 0.95 | PTGS1 (0.45) | PTGS1PTGS2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL7053269 | 0.89 | FFAR4 (0.47) | PTGS1PTGS2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL3962791 | 0.89 | FFAR4 (0.51) | PTGS1PTGS2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL2494888 | 0.88 | PTGS1 (0.40) | PTGS1PTGS2ALDH1A1ENPEPHSD17B10 | |
| SCHEMBL22972984 | 0.81 | MGLL (0.46) | PTGS1PTGS2ALDH1A1MEN1KMT2A | |
| SCHEMBL28536934 | 0.80 | PTGS1 (0.50) | PTGS1PTGS2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL25062606 | 0.80 | MGLL (0.48) | PTGS1PTGS2ALDH1A1GPR84MEN1 | |
| SCHEMBL17924843 | 0.80 | MGLL (0.34) | PTGS1PTGS2ALDH1A1 | |
| SCHEMBL25062322 | 0.80 | MGLL (0.48) | PTGS1PTGS2ALDH1A1GPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132295-B2 | Isotopically coded affinity markers 3 | BAYER AKTIENGESELLSCHAFT (DE) | 2006-11-07 | — | — | US | disclosed |
| US-20050049406-A1 | Isotopically coded affinity markers 3 | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-03 | — | — | US | disclosed |
| EP-1446665-A2 | ISOTOPICALLY CODED AFFINITY MARKERS 3 | Bayer HealthCare AG (DE) | 2004-08-18 | — | — | EP | disclosed |
| US-20030201208-A1 | Dynamic superparamagnetic markers | KOCH, MARTIN (DK) | 2003-10-30 | — | — | US | disclosed |
| WO-2003040288-A2 | ISOTOPICALLY CODED AFFINITY MARKERS 3 | BAYER HEALTHCARE AG (DE) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049406-A1 | Isotopically coded affinity markers 3 | IGFBP3, FABP3, LGALS3BP | PTGS1 4677/4885PTGS2 4648/4885FFAR4 4717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.