Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28258643 | 0.78 | PTGS1 (0.45) | PTGS1PTGS2ENPEPALDH1A1CYSLTR2 | |
| SCHEMBL326701 | 0.74 | PTGS1 (0.47) | PTGS1PTGS2ENPEPALDH1A1GABRP | |
| SCHEMBL5873778 | 0.74 | PTGS1 (0.47) | PTGS1PTGS2ENPEPALDH1A1GSTK1 | |
| SCHEMBL14360113 | 0.73 | ALDH1A1 (0.50) | ALDH1A1FFAR4 | |
| SCHEMBL28406949 | 0.73 | PTGS1 (0.50) | PTGS1PTGS2ALDH1A1GSTK1FFAR4 | |
| SCHEMBL2494888 | 0.71 | PTGS1 (0.40) | PTGS1PTGS2ENPEPALDH1A1GABRP | |
| SCHEMBL29505890 | 0.71 | KDM4E (0.49) | PTGS1PTGS2ENPEPALDH1A1GSTK1 | |
| SCHEMBL27690608 | 0.71 | ENPEP (0.44) | PTGS1PTGS2ENPEPALDH1A1GABRP | |
| SCHEMBL28536934 | 0.70 | PTGS1 (0.50) | PTGS1PTGS2ENPEPALDH1A1GSTK1 | |
| SCHEMBL7053269 | 0.70 | FFAR4 (0.47) | PTGS1PTGS2ALDH1A1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103384681-B | Binding agents | 霍夫曼-拉罗奇有限公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-107586340-A | To T cell activation antigen and the bispecific antibody and application method of specific for tumour antigen | 罗切格利卡特公司 | 2018-01-16 | — | — | CN | disclosed |
| CN-107531788-A | To HER2 and the three-specific antibody and application method of blood-brain barrier receptor-specific | 豪夫迈·罗氏有限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-103889452-B | Bispecific antibodies specific for T cell activating antigens and tumor antigens and methods of use | 罗切格利卡特公司 | 2017-11-03 | — | — | CN | disclosed |
| CN-103384825-B | Detection of post-translationally modified polypeptides by bivalent binding agents | 霍夫曼-拉罗奇有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-106432496-A | Anti-CD79B antibodies and immunoconjugates and methods of use | 健泰科生物技术公司 | 2017-02-22 | — | — | CN | disclosed |