Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020336 | 0.87 | RXRA (0.46) | NUDT1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL15677614 | 0.87 | NUDT1 (0.41) | NUDT1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL10203077 | 0.83 | NUDT1 (0.38) | NUDT1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL3966140 | 0.81 | NUDT1 (0.43) | NUDT1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL30329378 | 0.80 | LMNA (0.39) | L3MBTL1MEN1KMT2ALMNATSHR | |
| SCHEMBL14897410 | 0.79 | NUDT1 (0.46) | NUDT1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL30679589 | 0.79 | LMNA (0.38) | NUDT1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL14879888 | 0.79 | SCN9A (0.44) | L3MBTL1MEN1KMT2ALMNATSHR | |
| SCHEMBL29154 | 0.79 | NUDT1 (0.69) | NUDT1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29625490 | 0.79 | NUDT1 (0.69) | NUDT1L3MBTL1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912056-A | A kind of new benzoyl pyrimidine carbamide compounds and its preparation and application | 海南大学 | 2018-11-30 | — | — | CN | disclosed |