Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823619 | 0.84 | ANPEP (0.48) | ANPEP | |
| SCHEMBL2824115 | 0.84 | ANPEP (0.48) | ANPEPHDAC1ALDH1A1HDAC2TP53 | |
| SCHEMBL2825476 | 0.83 | TP53 (0.41) | HDAC1ALDH1A1KMT2APKMSMN1; SMN2 | |
| SCHEMBL2825413 | 0.80 | ALDH1A1 (0.54) | HDAC1HDAC3HDAC8HDAC5ALDH1A1 | |
| SCHEMBL29456287 | 0.80 | ALDH1A1 (0.54) | HDAC1HDAC3HDAC8HDAC5ALDH1A1 | |
| SCHEMBL4296538 | 0.76 | ALDH1A1 (0.41) | ANPEPALDH1A1KMT2APKMSMN1; SMN2 | |
| SCHEMBL2824816 | 0.75 | MAPT (0.44) | ANPEPHDAC1HDAC3HDAC8HDAC5 | |
| SCHEMBL787119 | 0.75 | PGR (0.54) | ANPEPHDAC1HDAC3HDAC8HDAC5 | |
| SCHEMBL31259107 | 0.73 | SCN9A (0.42) | ANPEPHDAC1HDAC3HDAC8HDAC5 | |
| SCHEMBL22667344 | 0.71 | ALDH1A1 (0.50) | ALDH1A1KMT2APKMSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799643-B1 | INDOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA SA (BE) | 2010-09-22 | — | — | EP | claimed |
| US-7632856-B2 | Indolone derivatives, processes for preparing them and their uses | UCB PHARMA, S.A. (BE) | 2009-12-15 | — | — | US | claimed |
| US-20090012147-A1 | Indolone Derivatives, Processes For Preparing Them And Their Uses | UCB PHARMA, S.A. (BE) | 2009-01-08 | — | — | US | claimed |
| EP-1799643-A1 | INDOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2007-06-27 | — | — | EP | claimed |
| WO-2006008067-A1 | INDOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2006-01-26 | — | — | WO | claimed |
| EP-1799643-B1 | INDOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA SA (BE) | 2010-09-22 | — | — | EP | disclosed |
| US-7632856-B2 | Indolone derivatives, processes for preparing them and their uses | UCB PHARMA, S.A. (BE) | 2009-12-15 | — | — | US | disclosed |
| US-20090012147-A1 | Indolone Derivatives, Processes For Preparing Them And Their Uses | UCB PHARMA, S.A. (BE) | 2009-01-08 | — | — | US | disclosed |
| EP-1799643-A1 | INDOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006008067-A1 | INDOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012147-A1 | Indolone Derivatives, Processes For Preparing Them And Their Uses | IDO1, IDO2, HTR3C | ANPEP 2230/4885HDAC1 3593/4885HDAC3 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.