Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | LMNA | P02545 | 8/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | BCL6 | P41182 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 2/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28257851 | 0.86 | MAPT (0.61) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL28259441 | 0.82 | RAB9A (0.72) | RAB9ANPC1MAOAMAOBMAPT | |
| SCHEMBL14423726 | 0.81 | KMT2A (0.59) | RAB9ANPC1MAOAMAOBMAPT | |
| SCHEMBL1520437 | 0.81 | RAB9A (1.00) | RAB9ANPC1MAOAMAOBMAPT | |
| SCHEMBL28259456 | 0.80 | RAB9A (0.72) | RAB9ANPC1MAOAMAOBMAPT | |
| SCHEMBL6965791 | 0.80 | LMNA (0.74) | RAB9ANPC1MAOAMAOBMAPT | |
| SCHEMBL28866630 | 0.80 | RAB9A (0.72) | RAB9ANPC1MAOAMAOBMAPT | |
| SCHEMBL28259440 | 0.80 | ALDH1A1 (1.00) | RAB9ANPC1MAOAMAOBMAPT | |
| SCHEMBL28257891 | 0.79 | RAB9A (0.67) | RAB9ANPC1MAOAMAOBMAPT | |
| SCHEMBL28257850 | 0.77 | MAPT (0.51) | MAPTLMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863876-A | A kind of thiourea and preparation method and application with gibberellin function | 中国农业大学 | 2018-11-23 | — | — | CN | disclosed |