SCHEMBL28260337

SCHEMBL28260337

NS(=O)(=O)c1cc(C(=O)O)c(Cl)c([N+](=O)[O-])c1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C19 P33261 1/20 0.57
CA2 P00918 10/20 0.57
CA12 O43570 9/20 0.57
CA9 Q16790 9/20 0.57
CA1 P00915 8/20 0.57
VCAM1 P19320 1/20 0.54
MAPT P10636 3/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SLC25A1 P53007 1/20 0.45
IDO1 P14902 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5870779 0.84 VCAM1 (0.68) ALDH1A1CA2CA12CA9CA1
SCHEMBL9795946 0.80 CA2 (0.65) ALDH1A1CA2CA12CA9CA1
SCHEMBL29787232 0.80 CA2 (0.65) ALDH1A1CA2CA12CA9CA1
Hydrochloric Acid SCHEMBL11779151 0.78 CA2 (0.63) ALDH1A1CA2CA12CA9CA1
SCHEMBL25354581 0.78 VCAM1 (0.60) ALDH1A1CA2CA12CA9CA1
SCHEMBL29747930 0.78 VCAM1 (0.60) ALDH1A1CA2CA12CA9CA1
SCHEMBL1494608 0.77 CYP3A4 (0.52) ALDH1A1CYP1A2CYP2D6CYP2C19VCAM1
SCHEMBL2535790 0.77 CA2 (0.56) ALDH1A1CYP1A2CYP2D6CYP2C19CA2
SCHEMBL1487913 0.76 CA1 (0.53) ALDH1A1CYP1A2CYP2D6CYP2C19CA2
SCHEMBL12603011 0.75 GPR35 (0.53) ALDH1A1CYP1A2CYP2D6CYP2C19CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109761944-A A kind of chrysin amide derivatives and preparation method thereof and medical usage 武汉翼博济生生物科技有限公司 2019-05-17 CN disclosed
CN-108963389-A It is a kind of for lithium-air battery can gelling system and its preparation method and application 北京师范大学 2018-12-07 CN disclosed
CN-108962627-A A kind of supercapacitor or capacitor batteries of organic system 北京师范大学 2018-12-07 CN disclosed