SCHEMBL28261306

SCHEMBL28261306

Cc1cc2occc2c(C)c1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
ADORA3 P0DMS8 3/20 0.36
CYP1A1 P04798 2/20 0.36
CYP2A6 P11509 2/20 0.36
CYP1A2 P05177 1/20 0.36
PGR P06401 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
KCNA2 P16389 1/20 0.36
TSHR P16473 1/20 0.36
MAOA P21397 1/20 0.36
CYP2C19 P33261 1/20 0.36
CYP1B1 Q16678 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HPGD P15428 2/20 0.36
THRB P10828 1/20 0.36
MAPK1 P28482 1/20 0.36
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28027394 0.81 PDE3B (0.34) CYP3A4KDM4EALDH1A1ADORA3CYP1A1
SCHEMBL23729748 0.81 CYP3A4 (0.33) CYP3A4KDM4EALDH1A1ADORA3CYP1A1
SCHEMBL26080841 0.76 PAX8 (0.37) CYP3A4KDM4EALDH1A1ADORA3CYP1A1
SCHEMBL8404363 0.74 MAOA (0.38) CYP3A4KDM4EALDH1A1CYP1A1CYP2A6
SCHEMBL6819496 0.73 CYP2A6 (0.40) CYP3A4KDM4EALDH1A1ADORA3CYP1A1
SCHEMBL18029727 0.72 CYP3A4 (0.36) CYP3A4KDM4EALDH1A1ADORA3CYP1A1
SCHEMBL30973539 0.70 CYP3A4 (0.45) CYP3A4KDM4EALDH1A1ADORA3CYP1A1
SCHEMBL4951315 0.70 FTO (0.53) CYP3A4KDM4EADORA3CYP1A1MAOA
SCHEMBL827878 0.70 AHR (0.41) CYP3A4KDM4EALDH1A1ADORA3CYP1A1
SCHEMBL31292049 0.70 FTO (0.53) CYP3A4KDM4EADORA3CYP1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110462465-A Liquid-crystal composition, liquid crystal cured film and its manufacturing method ZEON CORP 2019-11-15 CN disclosed
CN-110392850-A Liquid crystal cured film and its manufacturing method 日本瑞翁株式会社 2019-10-29 CN disclosed
CN-110088152-A The manufacturing method of mixture, macromolecule, optical film, optically anisotropic body, polarizing film, display device and antireflection film and mixture 日本瑞翁株式会社 2019-08-02 CN disclosed
CN-110072854-A Polymerizable compound, mixture, macromolecule, optical film, optically anisotropic body, polarizing film, display device and antireflection film 日本瑞翁株式会社 2019-07-30 CN disclosed
CN-110003008-A Mixture and compound 日本瑞翁株式会社 2019-07-12 CN disclosed
CN-109997061-A Optical laminate, circular polarizing disk, touch panel and image display device 日本瑞翁株式会社 2019-07-09 CN disclosed
CN-107400100-B Polymerizable compound, mixture, composition, polymer, film, optically anisotropic body, polarizing plate, and display device 日本瑞翁株式会社 2019-03-29 CN disclosed
CN-109477926-A Optically anisotropic laminate, polarizing plate, and image display device 日本瑞翁株式会社 2019-03-15 CN disclosed
CN-109071474-A Method for producing polymerizable compound, halide, and mixture 日本瑞翁株式会社 2018-12-21 CN disclosed
CN-109072082-A The manufacturing method of liquid crystalline composition, liquid crystal cured layer and the liquid crystal cured layer 日本瑞翁株式会社 2018-12-21 CN disclosed
CN-108885292-A Optical anisotropic layer and its manufacturing method, optical anisotropic layer stack and its manufacturing method, optical anisotropy transfer article, polarizing film and image display device 日本瑞翁株式会社 2018-11-23 CN disclosed