SCHEMBL2826182

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2823879	0.90	TOP2A (0.44)	TOP2AHDAC1HDAC8HDAC6SMO
	SCHEMBL2825623	0.86	TOP2A (0.46)	ADRB2ADRB1ADRB3TOP2AHDAC1
	SCHEMBL2822560	0.84	TOP2A (0.50)	ADRB2ADRB1ADRB3TOP2AHDAC1
	SCHEMBL2825250	0.82	GAA (0.49)	TOP2ASMOMAPTALDH1A1
	SCHEMBL2826651	0.82	DGAT1 (0.42)	TOP2ASMOMAPTALDH1A1
	SCHEMBL2823636	0.77	TOP2A (0.47)	TOP2AHDAC1HDAC8HDAC6SCN10A
	SCHEMBL2823220	0.77	TOP2A (0.50)	TOP2AHDAC1HDAC8HDAC6SCN10A
	SCHEMBL2824534	0.76	TARBP2 (0.49)	TOP2ASMOMAPTALDH1A1
	SCHEMBL2823778	0.76	PTPN1 (0.46)	TOP2AHDAC1HDAC8HDAC6KCNH2
	SCHEMBL2822676	0.76	XDH (0.61)	TOP2AMEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.