Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.72 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TPST2 | O60704 | 2/20 | 0.42 |
| ▸ | SULT1E1 | P49888 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358403 | 0.84 | PTPN1 (1.00) | PTPN1ERN1MEN1POLBKMT2A | |
| SCHEMBL5708656 | 0.84 | PTPN1 (1.00) | PTPN1ERN1MEN1POLBKMT2A | |
| SCHEMBL23887130 | 0.81 | PTPN1 (0.72) | PTPN1ERN1MEN1POLBKMT2A | |
| SCHEMBL29956932 | 0.79 | PTPN1 (0.68) | PTPN1ERN1MEN1POLBKMT2A | |
| SCHEMBL29246655 | 0.78 | PTPN1 (0.43) | PTPN1MEN1POLBKMT2ATPST2 | |
| SCHEMBL29956402 | 0.77 | PTPN1 (0.65) | PTPN1MEN1POLBKMT2ATPST2 | |
| SCHEMBL28262152 | 0.77 | PTPN1 (0.65) | PTPN1MEN1POLBKMT2ATPST2 | |
| SCHEMBL30307600 | 0.74 | PTPN1 (0.62) | PTPN1MEN1POLBKMT2AMAOA | |
| SCHEMBL7027357 | 0.72 | PTPN1 (0.60) | PTPN1MEN1POLBKMT2AMAOA | |
| SCHEMBL28295389 | 0.71 | PTPN1 (0.78) | PTPN1ERN1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |