SCHEMBL5708656

SCHEMBL5708656

O=Cc1coc2c(Cl)cc(Cl)cc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 13/20 1.00
TPST2 O60704 2/20 0.46
SULT1E1 P49888 2/20 0.46
MEN1 O00255 1/20 0.45
POLB P06746 1/20 0.45
KMT2A Q03164 1/20 0.45
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
ERN1 O75460 1/20 0.41
PTPN2 P17706 2/20 0.40
PDE10A Q9Y233 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295389 0.88 PTPN1 (0.78) PTPN1TPST2SULT1E1MEN1POLB
SCHEMBL29955707 0.84 PTPN1 (0.72) PTPN1TPST2SULT1E1MEN1POLB
SCHEMBL29956932 0.81 PTPN1 (0.68) PTPN1TPST2SULT1E1MEN1POLB
SCHEMBL28262152 0.79 PTPN1 (0.65) PTPN1TPST2SULT1E1MEN1POLB
SCHEMBL29956402 0.79 PTPN1 (0.65) PTPN1TPST2SULT1E1MEN1POLB
SCHEMBL7026584 0.78 PTPN1 (0.64) PTPN1TPST2SULT1E1POLBKMT2A
SCHEMBL30307601 0.77 PTPN1 (0.62) PTPN1MEN1POLBKMT2AMAOA
SCHEMBL8171800 0.76 PTPN1 (0.61) PTPN1TPST2SULT1E1MEN1KMT2A
SCHEMBL5363245 0.73 PTPN1 (1.00) PTPN1POLBKMT2AMAOAMAOB
SCHEMBL11541084 0.73 PTPN1 (0.58) PTPN1TPST2SULT1E1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260128372-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG CHEMICAL LTD (KR) 2026-05-07 US disclosed
EP-4576305-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG CHEM, LTD. (KR) 2025-06-25 EP disclosed
CN-120153509-A Nonaqueous electrolyte for lithium secondary battery and lithium secondary battery comprising same 株式会社LG化学 2025-06-13 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-9902710-B2 Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A) EXONHIT THERAPEUTICS, SA (FR) 2018-02-27 US disclosed
US-20160264549-A1 SUBSTITUTED 6, 7-DIALKOXY-3-ISOQUINOLINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE 10A) EXONHIT THERAPEUTICS, SA (FR) 2016-09-15 US disclosed
US-9200016-B2 Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A) ALLERGAN, INC. (US) 2015-12-01 US disclosed
US-20150158895-A1 SUBSTITUTED 6, 7-DIALKOXY-3-ISOQUINOLINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE 10A) ALLERGAN, INC. (US) 2015-06-11 US disclosed
US-20120316192-A1 SUBSTITUTED INDOLO [2,3-A] QUINOLIZINES MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2012-12-13 US disclosed
EP-2532664-A1 Substituted indolo [2,3-a] quinolizines in the treatment of cancer Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2012-12-12 EP disclosed
US-20040063157-A1 Pharmacophore recombination for the identification of small molecule drug lead compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-04-01 US disclosed
US-20020115107-A1 Pharmacophore recombination for the identification of small molecule drug lead compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-08-22 US disclosed
US-6344334-B1 DETECTION OF LEAD DRUG LIGANDS SUCH AS PROTEINS, NUCLEIC ACIDS OR SACCHARIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-02-05 US disclosed
US-6344330-B1 DETECTION OF LEAD DRUG LIGANDS SUCH AS PROTEINS, NUCLEIC ACIDS OR SACCHARIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-02-05 US disclosed
EP-1066522-A1 PHARMACOPHORE RECOMBINATION FOR THE IDENTIFICATION OF SMALL MOLECULE DRUG LEAD COMPOUNDS The Regents of the University of California (US) 2001-01-10 EP disclosed
WO-2000053313-A2 LANTHANIDE CATALYSTS FOR SYNTHESIS OF COMPOUNDS AND COMBINATORIAL LIBRARIES ARQULE, INC. (US) 2000-09-14 WO disclosed
WO-1999049314-A9 PHARMACOPHORE RECOMBINATION FOR THE IDENTIFICATION OF SMALL MOLECULE DRUG LEAD COMPOUNDS UNIV CALIFORNIA (US) 1999-11-18 WO disclosed
WO-1999049314-A1 PHARMACOPHORE RECOMBINATION FOR THE IDENTIFICATION OF SMALL MOLECULE DRUG LEAD COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-09-30 WO disclosed
US-4320133-A Penicillins and their antibacterial use SANDOZ LTD. (CH) 1982-03-16 US disclosed
EP-0003115-A1 Penicillins, per se and for use as antibacterially active antibiotics and their production SANDOZ AG (CH) 1979-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120316192-A1 SUBSTITUTED INDOLO [2,3-A] QUINOLIZINES BOD1L1, ACIN1, CDC25C PTPN1 1437/4885TPST2 598/4885SULT1E1 1090/4885
US-20160264549-A1 SUBSTITUTED 6, 7-DIALKOXY-3-ISOQUINOLINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE 10A) PDE9A, PDE10A, PDE6A PTPN1 770/4885TPST2 2142/4885SULT1E1 961/4885
US-20260128372-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME CLCN2, CLIC1, RER1 PTPN1 107/4885TPST2 4116/4885SULT1E1 1061/4885
US-20150158895-A1 SUBSTITUTED 6, 7-DIALKOXY-3-ISOQUINOLINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE 10A) PDE9A, PDE10A, PDE6A PTPN1 770/4885TPST2 2142/4885SULT1E1 961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.