Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28391148 | 0.84 | APP (0.48) | APPMAPK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28255462 | 0.81 | LOXL2 (0.43) | TDP1ALDH1A1CYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL6579959 | 0.80 | ABCG2 (0.41) | APPTDP1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL7755200 | 0.80 | ALDH1A1 (0.42) | TDP1ALDH1A1CYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL160600 | 0.79 | ENPP1 (0.39) | APPTDP1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL2083970 | 0.78 | ALDH1A1 (0.39) | TDP1MAPK1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL15777410 | 0.76 | ENPP1 (0.36) | ALDH1A1SMN1; SMN2KDM4ENPC1NFKB1 | |
| SCHEMBL13145980 | 0.76 | CA1 (0.44) | APPALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL10708276 | 0.74 | TDP1 (0.61) | APPTDP1MAPK1ALDH1A1CYP3A4 | |
| SCHEMBL24561 | 0.74 | TDP1 (0.67) | APPTDP1MAPK1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929243-A | A kind of diamine monomer and its preparation method and application containing asymmetric fluorophore structure | 吉林大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-108912003-A | A kind of diacid monomer and its preparation method and application containing asymmetric fluorophore structure | 吉林大学 | 2018-11-30 | — | — | CN | disclosed |