Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 13/20 | 0.43 |
| ▸ | PPARD | Q03181 | 10/20 | 0.43 |
| ▸ | PPARG | P37231 | 8/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | FABP2 | P12104 | 2/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819683 | 0.90 | KLKB1 (0.37) | BCL9CTNNB1PPARAPPARDKLKB1 | |
| SCHEMBL2823535 | 0.87 | PPARG (0.44) | PPARAPPARDPPARGTBXAS1KLKB1 | |
| SCHEMBL2818635 | 0.87 | PPARG (0.42) | PPARAPPARDPPARGTBXAS1FABP2 | |
| SCHEMBL2819470 | 0.87 | L3MBTL1 (0.47) | BCL9CTNNB1PPARAPPARDPPARG | |
| SCHEMBL2820265 | 0.86 | PPARA (0.53) | PPARAPPARDPPARGTBXAS1FABP2 | |
| SCHEMBL2819197 | 0.86 | PPARA (0.46) | PPARAPPARDPPARGTBXAS1FABP2 | |
| SCHEMBL2823007 | 0.85 | THRB (0.44) | PPARAPPARDPPARGMAOB | |
| SCHEMBL2819333 | 0.85 | PPARG (0.46) | PPARAPPARDPPARGTBXAS1 | |
| SCHEMBL2821029 | 0.84 | TBXAS1 (0.39) | TBXAS1KLKB1SLC22A12ALDH1A1SMN1; SMN2 | |
| SCHEMBL2819374 | 0.84 | TBXAS1 (0.42) | PPARAPPARDPPARGTBXAS1FABP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | claimed |
| WO-2010071813-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-α | ARYX THERAPEUTICS, INC. (US) | 2010-06-24 | — | — | WO | claimed |
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | disclosed |
| WO-2010071813-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-α | ARYX THERAPEUTICS, INC. (US) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | PPARA, PPARD, PPARG | BCL9 3218/4885CTNNB1 2027/4885PPARA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.