Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.68 |
| ▸ | CASP3 | P42574 | 2/20 | 0.65 |
| ▸ | CASP2 | P42575 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FER | P16591 | 1/20 | 0.45 |
| ▸ | LTK | P29376 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263 | 0.88 | CASP3 (0.81) | CASP3CASP7TTRCES1APP | |
| SCHEMBL29511191 | 0.88 | CASP3 (0.81) | CASP3CASP7TTRCES1APP | |
| Hydrogen Sulfide SCHEMBL11121709 | 0.85 | CASP3 (0.77) | CASP3TTRCES1APPMEN1 | |
| Water SCHEMBL9398503 | 0.85 | CASP3 (0.77) | CASP3CASP7TTRCES1APP | |
| SCHEMBL29025703 | 0.85 | CASP3 (0.77) | CASP3CASP7TTRCES1APP | |
| Hydrochloric Acid SCHEMBL7736926 | 0.85 | CASP3 (0.77) | CASP3CASP7TTRCES1APP | |
| Hydrogen Sulfide SCHEMBL11098631 | 0.85 | CASP3 (0.77) | CASP3TTRCES1APPMEN1 | |
| Iodide SCHEMBL30725965 | 0.85 | CASP3 (0.77) | CASP3CASP7TTRCES1APP | |
| Phthalimide SCHEMBL23063638 | 0.83 | GSK3B (0.88) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL11040503 | 0.83 | GSK3B (1.00) | GSK3BCASP3CASP2CASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921970-A | NITRATION OR PHTHALIMIDES | GENERAL ELECTRIC COMPANY (US) | 1990-05-01 | — | — | US | disclosed |