Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.77 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263 | 0.97 | CASP3 (0.81) | CASP3TTRCES1APPMEN1 | |
| SCHEMBL29511191 | 0.97 | CASP3 (0.81) | CASP3TTRCES1APPMEN1 | |
| Hydrochloric Acid SCHEMBL7736926 | 0.94 | CASP3 (0.77) | CASP3TTRCES1APPMEN1 | |
| SCHEMBL29025703 | 0.94 | CASP3 (0.77) | CASP3TTRCES1APPMEN1 | |
| Water SCHEMBL9398503 | 0.94 | CASP3 (0.77) | CASP3TTRCES1APPMEN1 | |
| Hydrogen Sulfide SCHEMBL11121709 | 0.94 | CASP3 (0.77) | CASP3TTRCES1APPMEN1 | |
| Hydrogen Sulfide SCHEMBL11098631 | 0.94 | CASP3 (0.77) | CASP3TTRCES1APPMEN1 | |
| SCHEMBL21196435 | 0.87 | CASP3 (0.68) | CASP3TTRCES1APPMEN1 | |
| SCHEMBL13442852 | 0.87 | CASP3 (1.00) | CASP3TTRCES1APPMEN1 | |
| Phthalimide SCHEMBL10397202 | 0.85 | GSK3B (0.68) | CASP3TTRCES1APPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117342998-A | Diamine monomer containing N-aminophthalimide structure, preparation method thereof, polyimide compound and application | 浙江工业大学 | 2024-01-05 | — | — | CN | disclosed |