Ethane

Ethane

SCHEMBL28263202

CC.Nc1c(F)c(F)c(S(=O)(=O)O)c(F)c1F

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 11/20 0.39
CA2 P00918 11/20 0.39
CA12 O43570 8/20 0.39
CA7 P43166 8/20 0.39
CA13 Q8N1Q1 8/20 0.39
F2 P00734 3/20 0.35
PRSS1 P07477 3/20 0.35
PRSS2 P07478 3/20 0.35
PRSS3 P35030 3/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34
DAPK1 P53355 1/20 0.34
CA9 Q16790 3/20 0.33
CA3 P07451 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
CA5A P35218 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8154017 0.95 CA1 (0.42) CA1CA2CA12CA7CA13
SCHEMBL18594452 0.91 CA1 (0.44) CA1CA2CA12CA7CA13
SCHEMBL18594499 0.85 CA1 (0.34) CA1CA2CA12CA7CA13
SCHEMBL9178730 0.83 CA1 (0.46) CA1CA2CA12CA7CA13
SCHEMBL2875483 0.82 CA2 (0.48) CA1CA2CA12CA7CA13
Sulfuric Acid SCHEMBL8646807 0.79 CA5A (0.40) CA1CA2CA12CA7CA13
SCHEMBL36242 0.79 CA2 (0.52) CA1CA2CA12CA7CA13
Ammonia Solution, Strong SCHEMBL21384843 0.76 CA2 (0.50) CA1CA2CA12CA7CA13
SCHEMBL21522351 0.76 CA2 (0.50) CA1CA2CA12CA7CA13
SCHEMBL21522549 0.76 CA2 (0.50) CA1CA2CA12CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105504154-B A kind of hydrophobic associated polymer and preparation method thereof 四川光亚聚合物化工有限公司 2019-01-04 CN disclosed