SCHEMBL28263418

SCHEMBL28263418

Cc1cc(C(O)c2cc(C)cc(C(C)(C)C)c2)cc(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
POLB P06746 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 2/20 0.37
TYR P14679 2/20 0.37
CA2 P00918 1/20 0.37
TACR1 P25103 1/20 0.36
TSHR P16473 2/20 0.36
HSPA5 P11021 1/20 0.34
CYP2C19 P33261 4/20 0.33
CYP2C9 P11712 3/20 0.33
HTR1D P28221 2/20 0.33
HIF1A Q16665 2/20 0.33
HTR1B P28222 1/20 0.33
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
HSD17B10 Q99714 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5051531 0.80 GABRA1 (0.39) RXRARXRBGABRA1GABRB2POLB
SCHEMBL7082656 0.80 POLB (0.38) RXRARXRBGABRA1GABRB2POLB
SCHEMBL5178685 0.80 ALDH1A1 (0.37) RXRARXRBALDH1A1TSHRHSD17B10
SCHEMBL8107856 0.79 RXRA (0.35) RXRARXRBGABRA1GABRB2POLB
SCHEMBL21695850 0.79 RXRA (0.35) RXRARXRBGABRA1GABRB2POLB
SCHEMBL15836404 0.78 POLB (0.37) RXRARXRBGABRA1GABRB2POLB
SCHEMBL3584509 0.78 ALDH1A1 (0.45) POLBSMN1; SMN2ALDH1A1TYRCA2
SCHEMBL2908551 0.77 GABRA1 (0.43) RXRARXRBGABRA1GABRB2POLB
SCHEMBL2526222 0.77 GABRA1 (0.43) RXRARXRBGABRA1GABRB2POLB
SCHEMBL1655430 0.75 GABRA1 (0.55) RXRARXRBGABRA1GABRB2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110036047-A METHACRYLIC COPOLYMER AND MOLDED ARTICLE 株式会社可乐丽 2019-07-19 CN disclosed
CN-106459554-B Methacrylic resin composition 株式会社可乐丽 2018-12-21 CN disclosed