Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 7/20 | 0.60 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28262980 | 0.84 | PDK2 (0.44) | PDK2MLNRKMT2ALMNASMN1; SMN2 | |
| SCHEMBL22624637 | 0.80 | PDK2 (0.62) | PDK2HSD17B1HSD17B2MLNRLMNA | |
| SCHEMBL3916812 | 0.79 | PDK2 (0.59) | PDK2HSD17B1HSD17B2MLNR | |
| SCHEMBL28021721 | 0.79 | MGLL (0.57) | MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL19520529 | 0.78 | PDK2 (0.66) | PDK2HSD17B1HSD17B2MLNRMEN1 | |
| SCHEMBL6424264 | 0.76 | PDK2 (0.56) | PDK2HSD17B1HSD17B2MEN1KMT2A | |
| SCHEMBL28033000 | 0.76 | L3MBTL1 (0.60) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL27594938 | 0.76 | DRD2 (0.48) | — | |
| SCHEMBL27730541 | 0.76 | POLB (0.37) | PDK2LMNASMN1; SMN2 | |
| SCHEMBL5086341 | 0.75 | CNR2 (0.56) | PDK2HSD17B1HSD17B2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071490-A | Acyclic derivatives | 默克专利股份公司 | 2018-12-21 | — | — | CN | disclosed |