SCHEMBL28264157

SCHEMBL28264157

O=C(O)c1cc2c(Br)c(C(=O)O)c(C(=O)O)cc2c(Br)c1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
AKR1C3 P42330 2/20 0.39
AKR1C4 P17516 1/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
KDM4E B2RXH2 2/20 0.38
GLA P06280 2/20 0.38
GPR35 Q9HC97 2/20 0.37
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
PRNP P04156 1/20 0.36
HSD17B10 Q99714 3/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP1A2 P05177 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
PTPN1 P18031 1/20 0.35
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22802151 0.85 TSHR (0.43) TSHRAKR1C3AKR1C4AKR1C2AKR1C1
SCHEMBL11563726 0.80 TSHR (0.43) TSHRAKR1C3AKR1C4AKR1C2AKR1C1
SCHEMBL195519 0.79 AKR1C3 (0.42) TSHRAKR1C3AKR1C4AKR1C2AKR1C1
SCHEMBL28218518 0.75 AKR1C3 (0.58) TSHRAKR1C3AKR1C4AKR1C2AKR1C1
SCHEMBL471893 0.74 CYP1A2 (0.39) TSHRAKR1C3AKR1C4AKR1C2AKR1C1
SCHEMBL30879499 0.74 CYP1A2 (0.39) TSHRAKR1C3AKR1C4AKR1C2AKR1C1
SCHEMBL6059483 0.73 CYP1A2 (0.48) TSHRAKR1C3AKR1C4AKR1C2AKR1C1
SCHEMBL29001030 0.72 HSD17B10 (0.40) TSHRAKR1C3KDM4EGLAGPR35
SCHEMBL11928183 0.71 CYP1A2 (0.46) TSHRAKR1C3AKR1C4AKR1C2AKR1C1
SCHEMBL32665215 0.71 KDM4E (0.47) KDM4EGLAHSD17B10ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109111441-A One kind is used for the fluorescent chemicals and its preparation method and application of TATP Visual retrieval 陕西师范大学 2019-01-01 CN claimed
US-20260022138-A1 METAL ORGANIC FRAMEWORKS FOR OLED APPLICATIONS AND METHODS OF USE CONWAY DAVID JONATHAN (US) 2026-01-22 US disclosed
CN-109111441-A One kind is used for the fluorescent chemicals and its preparation method and application of TATP Visual retrieval 陕西师范大学 2019-01-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022138-A1 METAL ORGANIC FRAMEWORKS FOR OLED APPLICATIONS AND METHODS OF USE TRPV3, VDR, TRPC3 TSHR 841/4885AKR1C3 2849/4885AKR1C4 2859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.