Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14785290 | 0.83 | RIPK1 (0.46) | RIPK1HTTSMN1; SMN2CCR4LMNA | |
| SCHEMBL24048341 | 0.81 | RIPK1 (0.44) | RIPK1HTTATMSMN1; SMN2CCR4 | |
| SCHEMBL21082097 | 0.81 | ALDH1A1 (0.46) | IDO1HTTCLCN2MAPT | |
| SCHEMBL19295450 | 0.80 | IDO1 (0.38) | RIPK1IDO1HTTATMSMN1; SMN2 | |
| SCHEMBL13884338 | 0.78 | HTT (0.42) | IDO1HTTATMCYP2D6CA12 | |
| SCHEMBL12403838 | 0.78 | ADRA2B (0.42) | IDO1ATMCLCN2MAPT | |
| SCHEMBL14027354 | 0.78 | RIPK1 (0.42) | RIPK1HTTSMN1; SMN2CCR4LMNA | |
| SCHEMBL6685097 | 0.77 | RIPK1 (0.56) | RIPK1IDO1ESR1HTTSMN1; SMN2 | |
| SCHEMBL29881429 | 0.77 | IDO1 (0.52) | IDO1ESR1HTTATMMAPT | |
| SCHEMBL6251669 | 0.77 | IDO1 (0.52) | IDO1ESR1HTTATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071685-A | Terminal-modified conjugated diene polymer, rubber composition, and rubber article | 株式会社普利司通 | 2018-12-21 | — | — | CN | disclosed |