Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 7/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268291 | 0.87 | TSHR (0.37) | TSHRSMN1; SMN2 | |
| SCHEMBL348615 | 0.84 | TSHR (0.80) | TSHRSMN1; SMN2FDPSCA1CA2 | |
| SCHEMBL8391264 | 0.80 | TSHR (0.73) | TSHRSMN1; SMN2FDPSCA1CA2 | |
| SCHEMBL1410522 | 0.80 | TSHR (0.73) | TSHRSMN1; SMN2FDPSCA1CA2 | |
| SCHEMBL29291467 | 0.78 | TSHR (0.70) | TSHRSMN1; SMN2FDPSCA2ADH1B | |
| SCHEMBL10491642 | 0.78 | TSHR (0.70) | TSHRSMN1; SMN2FDPSCA2ADH1B | |
| SCHEMBL29291473 | 0.78 | TSHR (0.70) | TSHRSMN1; SMN2FDPSCA2ADH1B | |
| SCHEMBL2926136 | 0.78 | TSHR (0.70) | TSHRSMN1; SMN2FDPSCA2ADH1B | |
| SCHEMBL9257929 | 0.78 | TSHR (0.70) | TSHRSMN1; SMN2FDPSCA2ADH1B | |
| SCHEMBL28418848 | 0.78 | TSHR (0.70) | TSHRSMN1; SMN2FDPSCA2ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109600993-A | Anti-EGFR antibody drug conjugates | 艾伯维公司 | 2019-04-09 | — | — | CN | disclosed |
| CN-109562169-A | anti-CD 98 antibodies and antibody drug conjugates | 艾伯维公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109563167-A | ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | 艾伯维公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109071509-A | BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF ROR-GAMMA | 生命医药公司 | 2018-12-21 | — | — | CN | disclosed |