Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264024 | 0.87 | TAAR1 (0.45) | MAPTALDH1A1HTTKMT2ARAB9A | |
| SCHEMBL28265155 | 0.85 | PTGS1 (0.48) | MAPTALDH1A1HTTKMT2ARAB9A | |
| SCHEMBL12790851 | 0.80 | HTT (0.54) | MAPTALDH1A1HTTKMT2ARAB9A | |
| SCHEMBL2808423 | 0.78 | NR4A2 (0.55) | MAPTALDH1A1HTTKMT2ARAB9A | |
| SCHEMBL5539118 | 0.77 | BRD4 (0.45) | MAPTALDH1A1HTTKMT2AKDM4E | |
| SCHEMBL3668412 | 0.76 | ALDH1A1 (0.55) | MAPTALDH1A1HTTKMT2ARAB9A | |
| SCHEMBL3907147 | 0.75 | ALDH1A1 (0.51) | MAPTALDH1A1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL28672271 | 0.72 | KDM4E (0.50) | MAPTALDH1A1HTTKMT2ARAB9A | |
| Methylmalonic Acid SCHEMBL27562489 | 0.71 | ALDH1A1 (0.51) | MAPTALDH1A1HTTKMT2ARAB9A | |
| SCHEMBL21808985 | 0.71 | HTT (0.68) | MAPTALDH1A1HTTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108976186-A | A method of the four substituted furan class compound of preparation based on carbon-hydrogen link activation | 中国科学院大连化学物理研究所 | 2018-12-11 | — | — | CN | disclosed |